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topics mueller
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Present Studies
Basic Research
- molecular control of iron homeostasis by oxidative stress
- molecular control of oxygen
- signaling function, metabolism and compartmentalization of hydrogen peroxide
- peroxisomes as source of cellular oxidative stress: role in apoptosis,
redox-regulation and liver disease
- role of oxidative stress in NASH (non-alcoholic steatosis hepatitis)
- mechanisms of liver fibrosis
- alcohol-mediated cancerogenesis
Clinical Studies
- non-invasive diagnosis of fibrosis (liver, kidney)
- confounding factors of liver stiffness
- alcohol serum marker
- hepatic iron overload disorders
- diagnosis and treatment of alcoholic liver disease
Ultrasensitive detection of H2O2 in biological samples
Former Studies
- analysis of hydrogen peroxide in biological systems
- enzymology of catalase
- cell-cycle regulation and cell adhesion functions
- cell-cycle and chemotherapeutic agents
- oxygen burst cascade of neutrophils
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